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Medicine Interactions with Ortho Tri-Cyclen Lo

September 25th 2009 14:38
The oral contraceptive, Ortho Tri-Cyclen Lo, or Progestin/ Estrogen, is one of the more popular birth control pills. But, if you're taking other medications, you want to make sure that you are aware of the potential side effects and interactions between the contraceptive and the other medications, vitamins, or supplements you are taking.


It's best that you make sure to tell your healthcare provider what medications you're taking, so that he is aware of any possible drug interactions that you may have, so that you both know what to look for in case of complications.

You want to make sure that you don't use Ortho Tri-Cyclen Lo with aromatase inhibitors (e.g., anastrazole, exemestane), sodium tetradecyl sulfate, or troleandomycin, because you may suffer serious interactions.

You want to make sure that you tell your doctor if you're on any medicines that can control blood sugar levels and blood pressure, as well as medications for underactive thyroid. You want to make sure that your healthcare physician knows if you are taking raloxifene, tamoxifen, acetaminophen, ascorbic acid/vitamin C, atorvastatin, and any azole antifungals such as itraconazole/ketoconazole/vag inal miconazole.

You'll also find that some medications that you may be on can actually decrease the effectiveness of the contraceptive because they may decrease the birth control hormones in your body. If you're taking antibiotics such as ephalosporins, chloramphenicol, macrolides such as erythromycin, penicillins, and sulfas, you want to be careful, as well as if you take any HIV protease inhibitors such as amprenavir, nelfinavir, and ritonavir.


Some seizure medications may decrease the effectiveness of hte birth control pill as well, so if you're taking barbiturates, carbamazepine, phenytoin, lamotrigine, or topiramate, you want to make sure that your doctor is aware.

Other drugs such as aprepitant, bexarotene, bosentan, dapsone, felbamate, griseofulvin, modafinil, nevirapine, phenylbutazone, rifamycins (e.g., rifampin), and even St. John's wort, can also reduce the effectiveness of the contraceptive.

Because Ortho Tri-Cyclen Lo can speed up or slow down how fast other medications are removed in your body, it can affect your liver enzymes. Generally, acetaminophen (common to tylonal), aspirin, certain beta blockers, clofibrate, cyclosporine, morphine, corticosteroids (prednisolone), certain benzodiazepines (lorazepam/temazepam), and theophylline.

Although, there seem to be many drugs and medications that can cause interactions with Ortho Tri-Cyclen Lo birth control, there are actually many others that can potentially cause complications. The above drugs are just the more common that you will come across.

Just remember that you want to make sure that before you start any new medication, your doctor is aware of what medications you are currently taking.



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